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Discoidin domain receptor 2 (DDR2) regulates body size and fat metabolism in mice

✍ Scribed by Kawai, Ikuma; Matsumura, Hirokazu; Fujii, Wataru; Naito, Kunihiko; Kusakabe, Ken; Kiso, Yasuo; Kano, Kiyoshi

Book ID: 121483275
Publisher: Springer Netherlands
Year: 2013
Tongue: English
Weight: 503 KB
Volume: 23
Category: Article
ISSN: 0962-8819
DOI: 10.1007/s11248-013-9751-2

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## Abstract Discoidin domain receptor 2 (DDR2) belongs to receptor tyrosine kinase (RTK) family and is activated by collagen binding. Although the bone defects in __Ddr2__ null mice have been reported for a decade, the molecular mechanism remains unclear. This study sought to investigate the functi