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Direct Use of Esters in the Mukaiyama Aldol Reaction: A Powerful and Convenient Alternative to Aldehydes

โœ Scribed by Inamoto, Yoshihiro; Nishimoto, Yoshihiro; Yasuda, Makoto; Baba, Akio


Book ID
125960443
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
771 KB
Volume
14
Category
Article
ISSN
1523-7060

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๐Ÿ“œ SIMILAR VOLUMES


Use of chiral enolsilanes and chiral ald
โœ Christophe Delas; Olivier Blacque; Claude Moฤฑฬˆse ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 84 KB

In the presence of a catalytic amount of titanium(IV) isopropoxide, an aldol reaction is conducted between chiral enolsilanes formed by an allyltitanation reaction and chiral aldehydes to afford ketones in high yields. These ketones were reduced and esterified by a Tischtschenko reaction to obtain e