Asymmetric aldol-type reaction between both achiral ketene silyl acetals of acetic acid esters and aldehydes by the use of a chiral promoter
✍ Scribed by Teruaki Mukaiyama; Shū Kobayashi; Tetsuya Sano
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 510 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
Highly enantloselectlve aldol-type reactlon between achiral ketene sllyl acetals of acetrc acid
📜 SIMILAR VOLUMES
The title reaction with unsubstifufed and monosubstituted silyf ketene acetals proceeds with high enantioseiectivify, and in the latter case good dinstereoselecfivity favoring the anfi-/Chydrory-amethyl esters in all reported cases.
## A stoicbiometric Itmomtofthccbiral~1turntdouttos tlaxssivcly promote the aqmmehic aldol rcactioa of al&hy&s with cd silyl ethers and the rdowitlg asymmettic leductioa in om pot to affcrd syI&l3diols willlbighetity.