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Direct Tumor Invasion in Colon Cancer: Correlation with Tumor Spread and Survival

โœ Scribed by Siu Kin C. Wong; Bin B. Jalaludin; Christopher J. A. Henderson; Matthew J. Morgan; Angela S. Berthelsen; Michael M. Issac; Andrew Kneebone

Book ID
106323147
Publisher
Springer
Year
2008
Tongue
English
Weight
166 KB
Volume
51
Category
Article
ISSN
0012-3706

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## Abstract Thymidylate synthase (TS) is a key enzyme in folate metabolism, a pathway that is important in colorectal carcinogenesis. We investigated the role of functional polymorphisms in the __TS__ 5โ€ฒโ€UTR promoter enhancer region (__TSER__, 3 or 2 repeats of a 28โ€bp sequence) and the 3โ€ฒโ€UTR (__1