Patients with acute myocarditis and healthy volunteers were studied to assess the ability of T2 mapping to detect myocardial edema. The T2 maps detected global and regional edema in patients. T2 mapping may be an alternative to STIR images for detecting myocardial edema in patients with acute myocar
Direct T2 quantification to detect myocardial edema in patients with myocarditis and tako-tsubo cardiomyopathy
โ Scribed by Paaladinesh Thavendiranathan; Michael Walls; Shivraman Giri; David Verhaert; Orlando P Simonetti; Subha V Raman
- Publisher
- BioMed Central
- Year
- 2011
- Tongue
- English
- Weight
- 600 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1097-6647
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โฆ Synopsis
Background/objective
T2-weighted cardiovascular magnetic resonance (T2W-CMR) has shown utility in diseases such as myocarditis and tako-tsubo cardiomyopathy (TTCM) where myocardial edema may be the predominant pathological abnormality. Since these conditions may affect many myocardial regions, a more quantitative approach may help identify extent of myocardial involvement and reduce uncertainty in qualitative interpretation of T2W-CMR. We sought to evaluate the diagnostic utility of quantitative T2 mapping in patients presenting with acute myocarditis or TTCM.
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By cardiac MRI we investigated the relationship of resting myocardial blood flow (MBF) in hypertrophic cardiomyopathy (HCM) patients to important parameters of disease. MBF was quantified on pixel-by-pixel basis in 804 segments in 70 patients. Relative MBF negatively correlated with left-ventricular