Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-β-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the β-anomers of these nucleosides po
Direct synthesis, substitution, and structure of 1-(2′-deoxyβ-D-erythro-pentofuranosyl)-4-pentafluorophenylpyrimidin-2H-one
✍ Scribed by Mark P. Wallis; Ian D. Spiers; Carl H. Schwalbe; William Fraser
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 237 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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(2-Deoxy-D-erythro-pentofuranosyl)imidazole nucleosides have been synthesised by glycosylation of the sodium salt of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-3,5-di-O-p-toluoyl-alpha-D-erythro-pentofuranosyl chloride. Glycosylation of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-beta-D
The rate constants for the hydrolysis of several rubrt mted 9-(2-deoxy-B-D-erythro-pentofurenosyl)purines end 9-(l-rlkoxyethvl)purines firm ii measured at different concentrrtionb of-oxoniua ion. The effects that varying the polar nature of the l lkoxy group exerts on the hydrolysis of unsubstituted