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Direct Synthesis of β-Hydroxy-α-amino Acids via Diastereoselective Decarboxylative Aldol Reaction

✍ Scribed by Singjunla, Yuttapong; Baudoux, Jérôme; Rouden, Jacques


Book ID
125849106
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
386 KB
Volume
15
Category
Article
ISSN
1523-7060

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## Abstract An easily available and efficient chiral __N__,__N__′‐dioxide–nickel(II) complex catalyst has been developed for the direct catalytic asymmetric aldol reaction of α‐isothiocyanato imide with aldehydes which produces the products in morderate to high yields (up to 98 %) with excellent di