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Direct synthesis of 3,4-dihydro-2H-pyrido[1,2-a]pyrimidines, by addition reactions with 2-aminopyridines

✍ Scribed by John M Mellor; Glynn D Merriman; Helen Rataj; Gillian Reid


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
213 KB
Volume
37
Category
Article
ISSN
0040-4039

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## Abstract We report the condensation of substituted 2‐aminopyridines 5 with β‐ketocarboxylic esters in polyphosphoric acid. In this reaction were obtained together with the target compounds, 4__H__‐pyrido[1,2‐__a__]pyrirnidin‐4‐ones 6 also the pyridin‐2‐ones 7. All the compounds 7 were tested for