Direct synthesis of 2-oxazolines from carboxylic acids using 2-chloro-4,6-dimethoxy-1,3,5-triazine under mild conditions
β Scribed by B.P Bandgar; S.S Pandit
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 214 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Our study demonstrated that 4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methyl-morpholinium chloride (DMTMM) is a versatile coupling reagent for the synthesis of sterically-hindered peptidomimetics. It is superior to HBTU/HOBt and CDMT in controlling racemization and N-arylation, respectively.
## Abstract 2,4,6βTrichloroβ1,3,5βtriazine efficiently catalyzed the condensation reactions between 2βaminothiophenol and aromatic aldehydes to afford 2βarylbenzothiazolles in goodβtoβexcellent yields. Simple and mild reaction conditions, the use of a cheap catalyst and easy work up, and isolation