Direct separation of nadolol enantiomers on a Pirkle-type chiral stationary phase
β Scribed by A.M. Dyas; M.L. Robinson; A.F. Fell
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 369 KB
- Volume
- 586
- Category
- Article
- ISSN
- 1873-3778
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The direct separation of β€-aminoester enantiomers by HPLC on synthetic chiral stationary phases based on aacidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of different columns containing the stationary phase with opposite configurations and in the racemic f
## Abstract Amylopectinβ__tris__(phenylcarbamate) was synthesized and coated to aminopropylsilica to prepare chiral stationary phase. The chiral separations of fungicide enantiomers were performed by the CSP using highβperformance liquid chromatography. Mobile phase was __n__βhexane and isopropanol