This paper describes the enantiorecognition of (±)nicotine and (±)nornicotine by high-performance liquid chromatography using two derivatized cellulose chiral stationary phases (CSPs) operated in the normal phase mode. It was found that different substituents linked to the cellulose backbone signifi
Direct HPLC separation of β-aminoester enantiomers on totally synthetic chiral stationary phases
✍ Scribed by F. Gasparrini; I. D'Acquarica; C. Villani; C; Cimarelli; G. Palmieri
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 119 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0269-3879
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✦ Synopsis
The direct separation of -aminoester enantiomers by HPLC on synthetic chiral stationary phases based on aacidic derivative of trans 1,2-diaminocyclohexane as selector is described. The application of different columns containing the stationary phase with opposite configurations and in the racemic form to the determination of enantiomeric excess in chemically impure samples is demonstrated.
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