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Direct separation of in vivo and in vitro am3 revertants in transgenic mice carrying the phix174 am3, cs70 vector

✍ Scribed by Heinrich V. Malling; Robert R. Delongchamp

Book ID: 102190149
Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 256 KB
Volume: 37
Category: Article
ISSN: 0893-6692
DOI: 10.1002/em.1042

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## Abstract In mutation assays using transgenic mice, with recoverable vectors such as ΦX174 __am3, cs70,__ mutations originate from two sources: (1) in vivo mutations, that is, mutations that were fixed in the mouse, or (2) ex vivo mutations, that is, mutations that were fixed during recovery or p