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Direct resolution of enantiomers of basic imidazol-2-yl-substituted alcohols by gas chromatography on chirasil-val

โœ Scribed by Dr. John M. Briody; David Keenan; Graeme J. Nicholson; Bernhard Koppenhoefer


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
233 KB
Volume
5
Category
Article
ISSN
0899-0042

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โœ Koppenhoefer, B. ;Allmendinger, H. ;Bayer, E. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 338 KB

Several dipeptides have been separated into stereoisomers (enantiomers, diastereoisomers, sequential isomers) by GC on the chiral stationary phase Chirasil-Val. Sufficiently volatile N-TFA-dipeptide methyl esters have been formed by derivatization at ambient temperature, thus avoiding racemization (