Direct repression of the human IRF-3 promoter by E2F1
β Scribed by Hua-Guo Xu; Wei Ren; Li Zou; Yi Wang; Rui Jin; Guo-Ping Zhou
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 376 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0093-7711
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Pura is a ubiquitously expressed multifunctional nucleic acid-binding protein that is involved in many cellular processes including transcriptional regulation, the cell cycle, oncogenic transformation, and post-natal brain development. Previously, Pura protein was found to bind to E2F-1, inhibit E2F
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Dihydrofolate reductase activity is required for many biosynthetic pathways including nucleotide synthesis. Its expression is therefore central to cellular growth, and it has become a key target for cancer chemotherapy. Transcription of the dihydrofolate reductase gene is regulated with growth, bein