Metastatic melanoma still has a very poor prognosis since it withstands conventional therapies like surgery or chemotherapy. A paraneoplastic autoimmune manifestation of this disease is melanoma-associated retinopathy (MAR). MAR has been associated with prolonged survival and may be an early marker
Direct identification of tumor-associated peptide antigens
β Scribed by Engelhard, Victor H.
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 949 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0344-4325
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Serological identification of human tumor antigens
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract To improve tumor targeting in a subset of patients, where tumor cells do not express the wellβknown tumor antigens widely used in immunotherapy, we have developed a novel biotechnological tool. It is useful for tumors of various origins for the identification of tumorβassociated protein
## Abstract Screening cDNA libraries from solid human tumors with sera of autologous patients (SEREX) has proven to be a powerful approach to identifying tumor antigens recognized by the humoral arm of the immune system. In many cases, application of this methodology has led to the discovery of nov