Characterization and molecular biology of tumor-associated antigens
β Scribed by J. Thurin
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 936 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0952-7915
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Tumorβassociated antigen(s) from a specimen of human malignant melanoma and from spent culture medium of a melanoma cell line were extracted and purified. The incidence of antibody activity to these antigens, in sera from cancer patients with neoplasms of various histologic types, was h
We have previously prepared monoclonal antibodies (MAbs) against tumor vasculature using cultured rat tumor endothelial cells (TECs) isolated from solid KMT-17 tumors and identified 40 and 80 kDa antigens recognized by TES-17 and TES-23 MAbs, respectively. To clarify the nature of antigens on tumor