Direct formation of highly functionalized allylic organocopper reagents from allylic chlorides and acetates
โ Scribed by Stack, Douglas E.; Dawson, Bryan T.; Rieke, Reuben D.
- Book ID
- 126082447
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 948 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Highly reactive copper solutions have been prepared by the lithium naphthalide reduction of a copper(I) iodide/triphenyl-phosphine complex. These copper solutions react rapidly with functionalized alkyl halides to give organocopper reagents which have been effectively trapped with acid chlorides giv
Highly Stereoselective SN2' Reactions of Grignard Reagents Towards CF3-Containing Allylic Acetates. -The ฮณ-trifluoromethylated allylic acetates react with Grignard reagents in the presence of catalytic CuCN/TmsCl to form the products ( III) and (IV) resulting exclusively from an SN2' type reaction.