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Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

✍ Scribed by Mala K. Maini; Carolina Boni; Graham S. Ogg; Abigail S. King; Stephanie Reignat; Chun Kyon Lee; Juan R. Larrubia; George J.M. Webster; Andrew J. McMichael; Carlo Ferrari; Roger Williams; Diego Vergani; Antonio Bertoletti


Book ID
118521886
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
583 KB
Volume
117
Category
Article
ISSN
0016-5085

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Both strong antigenic avidity and acquisition of proper effector functions contribute to the efficacy of antiviral T cell responses. To correlate these parameters with the outcome of hepatitis C virus (HCV) infection, we characterized HCV-specific CD8 T cell lines isolated after immunomagnetic sorti