Direct TLC resolution of atenolol and pr
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Ravi Bhushan; Shivani Tanwar
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Article
📅
2008
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John Wiley and Sons
🌐
English
⚖ 148 KB
👁 1 views
## Abstract Direct resolution of racemic atenolol and propranolol into their enantiomers was achieved by normal phase TLC on silica gel plates impregnated with optically pure l‐tartaric acid, (__R__)‐mandelic acid and (–)‐erythromycin as chiral selectors. Different solvent systems were worked out t