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Direct effects of cholihergic stimulation on ventricular automaticity in guinea pig myocardium

✍ Scribed by David P. Rardon; John C. Bailey

Book ID
115669981
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
152 KB
Volume
49
Category
Article
ISSN
0002-9149

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The electrophysiological effects of urapidil, a new aradrenoceptor antagonist, were assessed in the reserpinized guinea-pig ventricular myocardium. Urapidil suppressed the maximal rate of rise (Vm~) of steady-state action potentials elicited by the fast responses at high concentrations independently