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Direct diastereoselective synthesis of (±)-cis- and (±)-trans-4-methylpipecolic acid and derivatives

✍ Scribed by Janine Cossy; Damien Belotti

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
64 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

±)-cis-or (±)-trans-4-Methylpipecolic acid and ester derivatives can be obtained directly by addition of electrophiles to a-lithiated N-Boc 4-methylpiperidine.

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