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Direct Determination of 1-Naphthol in Human Urine by Coupled-Column Liquid Chromatography with Fluorescence Detection

✍ Scribed by J.V. Sancho; R.A. Cabanes; F.J. López; F. Hernández

Book ID
111787872
Publisher
Springer
Year
2003
Tongue
English
Weight
264 KB
Volume
58
Category
Article
ISSN
0009-5893

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## Abstract A simple, specific and sensitive HPLC method has been developed for the determination of metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal standard) was achieved on an Ace C~18~ column (5 μm, 250 mm×4.6 mm id) using fluorescence detection with λ~ex~=2