Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo
β Scribed by Xiaoling Zhang; Changlong Yu; XuShi; Chao Zhang; Tingting Tang; Kerong Dai
- Book ID
- 116292143
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 746 KB
- Volume
- 341
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Chitosans of high molecular weights have emerged as efficient nonviral gene delivery systems, but the properties and efficiency of wellβdefined low molecular weight chitosans (<5 kDa) have not been studied. We therefore characterized DNA complexes of such low molecular we
## Abstract **Background** Lipidβbased vectors have been widely applied to __in vivo__ and __in vitro__ gene delivery. Disaccharides can effectively stabilize lipid membranes. This study examined whether disaccharides could enhance the transgene expression mediated by lipidβbased vectors. **Method