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Direct assignment of disulfide bonds by Edman degradation of selected peptide fragments

✍ Scribed by HANIU, MOITSURU ;ACKLIN, CHRISTINE ;KENNEY, WILLIAM C. ;ROHDE, MICHAEL F.


Book ID
115099605
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
484 KB
Volume
43
Category
Article
ISSN
0367-8377

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The determination of the primary structure of peptides and proteins is routine in many laboratories; however, many of the obtained sequences are incomplete or can be misinterpreted when the samples contain unusual amino acids. Here we report the development of an automated peptide sequenator coupled