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Direct and indirect recognition: the role of MHC antigens in graft rejection

✍ Scribed by Dina S Gould; Hugh Auchincloss Jr

Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
166 KB
Volume
20
Category
Article
ISSN
0167-5699

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T cells recognize foreign antigens in the form of peptide fragments resulting from antigen processing by antigen-presenting cells. In contrast to this indirect recognition, MHC molecules of foreign cells can be directly recognized by T cells. Direct recognition has for a long time been considered th