The exact process that leads to the eruption of autoimmune reactions against beta cells and the evolution of diabetes is not fully understood. Macrophages and T cells may launch an initial immune reaction against the pancreatic islets of Langerhans, provoking inflammation and destructive insulitis.
✦ LIBER ✦
The role of Fas ligand as an effector molecule in corneal graft rejection
✍ Scribed by Patrick M. Stuart; Xiatang Yin; Stacey Plambeck; Fan Pan; Thomas A. Ferguson
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 196 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
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## Abstract The role of CD95 ligand (FasL/Apo‐1L)‐expressing tumors in immunosuppression or immunopotentiation is controversial. CD95L‐transfected tumors induce immunopotentiation after vigorous neutrophil infiltration. Thus, the induction of neutrophil infiltration by CD95L seems to play an import