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Direct and Enantioselective Organocatalytic α-Chlorination of Aldehydes.

✍ Scribed by Michael P. Brochu; Sean P. Brown; David W. C. MacMillan


Publisher
John Wiley and Sons
Year
2004
Weight
166 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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## Halogenation O 0235 Direct Organocatalytic α-Fluorination of Aldehydes and Ketones. -A first protocol employs proline as the catalyst and Selectfluor as the electrophilic source of fluorine. The asymmetric induction is further investigated with various proline analogues (VII) and found to be ra