𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dipping into the Cytosol to Broaden the MHC Class II Peptide Repertoire

✍ Scribed by Lisa K. Denzin; Derek B. Sant’Angelo


Book ID
116570455
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
40 KB
Volume
22
Category
Article
ISSN
1074-7613

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


DM and DO shape the repertoire of peptid
✍ Lars Karlsson 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 117 KB

The presentation of antigenic peptides by MHC class II molecules is essential for activation of CD4+ T cells. The formation of most peptide-MHC-class-II complexes is influenced by the actions of two specialized accessory proteins--DM and DO--located in the endosomal/lysosomal system where peptide lo

How HLA-DM edits the MHC class II peptid
✍ Harald Kropshofer; Günter J. Hämmerling; Anne B. Vogt 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 637 KB

Loading of classical major histocompatibility complex (MHC) class II molecules with antigen-derived peptides is fast, efficient and highly selective in vivo, quite in contrast to in vitro findings with isolated class II proteins and synthetic peptides. Do accessory proteins speed up the loading proc