## Abstract Phenotypic accommodation is adaptive adjustment, without genetic change, of variable aspects of the phenotype following a novel input during development. Phenotypic accommodation can facilitate the evolution of novel morphology by alleviating the negative effects of change, and by givin
Diplopia and loss of accommodation due to chloroquine
β Scribed by Dr. Melvin L. Rubin; William C. Thomas Jr
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 613 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
β¦ Synopsis
Impaired visual accommodation is a frequently occurring complication of chloroquine therapy. The present report describes a patient whose ocular function was assessed serially during chloroquine administration. Impaired convergence and loss of accommodative amplitude developed several weeks after beginning chloroquine treatment; the magnitude of these alterations in ocular function was dose related. Chloroquine-induced changes persisted during therapy, but ocular function returned to pretreatment limits 1 week after discontinuing the drug.
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