𝔖 Bobbio Scriptorium
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Diphosphonates inhibit human osteoblast secretion and proliferation

✍ Scribed by M.A. Khokher; P. Dandona

Book ID
118949788
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
464 KB
Volume
38
Category
Article
ISSN
1532-8600

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## Abstract Recent data suggest that megakaryocytes (MKs) play a role in skeletal homeostasis. In vitro and in vivo data show that MKs stimulate osteoblast (OB) proliferation and inhibit osteoclast (OC) formation, thus favoring net bone deposition. There are several mouse models with dysregulated m