C-Terminal Parathyroid Hormone-Related Protein Inhibits Proliferation and Differentiation of Human Osteoblast-like Cells
✍ Scribed by Maria Eugenia Martínez; Adolfo García-Ocaña; Maravillas Sánchez; Sonia Medina; Teresa Del Campo; Alvaro Valin; Maria Jesus Sanchez-Cabezudo; Pedro Esbrit
- Book ID
- 111486079
- Publisher
- American Society for Bone and Mineral Research
- Year
- 1997
- Tongue
- English
- Weight
- 680 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0884-0431
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Parathyroid hormone (PTH) receptors and the biological response to PTH in osteoblasts have been shown to be influenced by glucocorticoids, growth factors, cytokines or PTH itself. Furthermore, components of extracellular matrix (ECM) appear to regulate the response to PTH as well. We investigated th
## Abstract The present study was performed to clarify second messenger signaling in parathyroid hormone (PTH)‐induced c‐fos gene expression, to characterize the participation of the c‐fos gene in the regulation of osteoblast proliferation and function as well as osteoclast‐like cell formation by P