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Dioxin Causes a Sustained Oxidative Stress Response in the Mouse

✍ Scribed by Howard G. Shertzer; Daniel W. Nebert; Alvaro Puga; Michelle Ary; David Sonntag; Kathleen Dixon; Lindsey J. Robinson; Eli Cianciolo; Timothy P. Dalton


Book ID
115583034
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
87 KB
Volume
253
Category
Article
ISSN
0006-291X

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Increased production of superoxide and nitric oxide may produce oxidative stress in the placenta by formation of the prooxidant peroxynitrite, which itself causes vascular dysfunction. Nitrotyrosine residues, which are a marker of peroxynitrite formation and action, are found in placental vessels of