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Telomeres Shorten in Response to Oxidative Stress in Mouse Skeletal Muscle Fibers

โœ Scribed by Ludlow, A. T.; Spangenburg, E. E.; Chin, E. R.; Cheng, W.-H.; Roth, S. M.


Book ID
121460010
Publisher
The Gerontological Society of America
Year
2014
Tongue
English
Weight
483 KB
Volume
69
Category
Article
ISSN
1079-5006

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## Abstract Amyotrophic lateral sclerosis (ALS) is caused by motor neuron loss in the spinal cord, but the mechanisms responsible are not known. Ubiquitous transgenic overexpression of copper/zinc superoxide dismutase (SOD1) mutations causing familial ALS (SOD1^mut^) leads to an ALS phenotype in mi