Immortalization of normal human fibrobla
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L. Bai; K. Mihara; Y. Kondo; M. Honma; M. Namba
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Article
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1993
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John Wiley and Sons
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French
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Normal human fibroblasts (the OUMS-24 strain), derived from a 6-week-old human embryo, were transformed (into the OUMS-24F line) and immortalized by repeated treatments (59 times) with 4-nitroquinoline I -oxide (4NQO). Treatment began during primary culture and ended at the 5 I st population doublin