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Diminution of N-methyl-d-aspartate-induced perturbation of neurotransmission by dexmedetomidine in the CA1 field of rat hippocampus in vitro

✍ Scribed by Minna Niittykoski; Antti Haapalinna; Jouni Sirviö

Book ID: 117470484
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 138 KB
Volume: 281
Category: Article
ISSN: 0304-3940
DOI: 10.1016/s0304-3940(00)00811-9

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## Abstract Among the different steroids found in the brain, pregnenolone sulfate (3β‐hydroxy‐5‐pregnen‐20‐one‐3‐sulfate; PREGS) is known to enhance hippocampal‐associated memory. The present study employs rat hippocampal slices to investigate the ability of PREGS to modulate long‐term potentiation