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Effects of riluzole on N-methyl-d-aspartate-induced tyrosine phosphorylation in the rat hippocampus

✍ Scribed by Agnès Peyclit; Hawa Keita; Philippe Juvin; Pascal Derkinderen; Fanny Jardinaud; Danielle Rouellé; Jorge Boczkowski; Jean-Marie Desmonts; Jean-Antoine Girault; Jean Mantz


Book ID
113997137
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
340 KB
Volume
903
Category
Article
ISSN
0006-8993

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This study investigated the modulatory actions of adenosine and ␥-aminobutyric acid (GABA) on several aspects of N-methyl-Daspartate (NMDA)-induced neurotoxicity, including neuronal loss, atrophy, necrosis, and calcium accumulation in the hippocampus. For this purpose, we combined unilateral intrahi