Dihydrotentoxin: A precursor of tentoxin or its degradation product?

✍ Scribed by Dr. B. Liebermann; W. Ihn

• Book ID: 102390928
• Publisher: John Wiley and Sons
• Year: 1988
• Tongue: English
• Weight: 454 KB
• Volume: 28
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.3620280109

✦ Synopsis

Besides tentoxin, dihydrotentoxin is produced by Alternaria alternata in similar quantities. Both peptides are excreted mainly into theculturemedium, with a low content (20-55 pg/g) being found in themycelium already of an early stage of fermentation. Tentoxin is not degraded during cultivation, therefore, dihydrotentoxin cannot be a decomposition product of the phytotoxin. During the isolation procedure, some tentoxin (10 to 15 %) and even more dihydrotentoxin (30-40 %) is lost. Incorporation of labelled dihydrotentoxin (14C, 15N) into tentoxin during fermentation allows the conclusion that the nonoxidized peptide is the precusor of tentoxin.