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Dihydrofolate reductase is present in brain

โœ Scribed by R. J. Pollock; S. Kaufman


Book ID
111170139
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
353 KB
Volume
30
Category
Article
ISSN
0022-3042

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๐Ÿ“œ SIMILAR VOLUMES


Mammalian brain dihydrofolate reductase
โœ R. Lynn; M. E. Rueter; R. W. Guynn ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 206 KB
Dihydrofolate reductase-activity in brai
โœ Ludwig, Rolf ;Frei, Eva ;Kimmig, Bernhard ;Brandeis, Werner E. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer-Verlag โš– 310 KB

The mechanism responsible for the toxic late effects of cranial irradiation, followed by the administration of systemic methotrexate (MTX) on brain tissue, is still under discussion. We studied the influence of X-irradiation on dihydrofolate reductase (E.C. 1.5.1.3) activity (DHFR), the enzyme inhib