๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli: Dihydrofolate monooxygenase activity

โœ Scribed by Martin Poe

Book ID
118854007
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
344 KB
Volume
54
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Site-specific mutagenesis of dihydrofola
Site-specific mutagenesis of dihydrofolate reductase from Escherichia coli
โœ Jin-Tann Chen; Ruth J. Mayer; Carol A. Fierke; Stephen J. Benkovic ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 441 KB

Two site-specific mutations of dihydrofolate reductase from Escherichiu coli based on the x-ray crystallographic structure were constructed. The first mutation (His-45 + Gln) is aimed at assessing the interaction between the imidazole moiety and the pyrophosphate backbone of NADPH. The second (Thr-1