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Diflubenzuron, a Benzoyl-Urea Insecticide, Is a Potent Inhibitor of TCDD-Induced CYP1A1 Expression in HepG2 Cells

โœ Scribed by N. Ledirac; C. Delescluse; P. Lesca; M.P. Piechocki; R.N. Hines; G. de Sousa; M. Pralavorio; R. Rahmani


Book ID
112267118
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
161 KB
Volume
164
Category
Article
ISSN
0041-008X

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Sudan III dye strongly induces CYP1A1 mR
โœ Marumi Ohno; Yoshinori Ikenaka; Mayumi Ishizuka ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 219 KB

## Abstract Sudan dyes possess a high affinity to the aryl hydrocarbon receptor (AHR) and potently induce its target genes, such as cytochrome P450 (CYP) 1A1, through unknown mechanisms. We investigated a detailed event occurring in cells after binding of Sudan dye to AHR in HepG2 cells. Treatment