Sudan III dye strongly induces CYP1A1 mR
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Marumi Ohno; Yoshinori Ikenaka; Mayumi Ishizuka
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Article
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2012
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John Wiley and Sons
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English
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## Abstract Sudan dyes possess a high affinity to the aryl hydrocarbon receptor (AHR) and potently induce its target genes, such as cytochrome P450 (CYP) 1A1, through unknown mechanisms. We investigated a detailed event occurring in cells after binding of Sudan dye to AHR in HepG2 cells. Treatment