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Diffusion of Nonoxynol-9 Into Human Semen In Vitro

✍ Scribed by Eric Chantler; Ivo L Gwanmesia; J.Malcolm Bruce


Book ID
117084783
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
82 KB
Volume
57
Category
Article
ISSN
0010-7824

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The spermicidal surfactant nonoxynol-9 (Igepal CO-630, GAF Corp.) and a potential impurity, lP-dioxane, were tested in the in vitro cell transformation assay using BALB/3T3 cells. Two treatment periods, 48 hr and 13 days, were used. Nonoxynol-9, tested at levels up to 10 pglml, did not induce transf