## Abstract High resolution 400 MHz ^1^H NMR spectra of red blood cell suspensions when measured using magic angle spinning (MAS) show two water resonances separated by 15 Hz. Based on addition of a paramagnetic Mn‐EDTA complex, measurement of relaxation times and variation of extracellular H~2~O/D
Diffusion in red blood cell suspensions: Separation of the intracellular and extracellular NMR sodium signal
✍ Scribed by J. W. C. van der Veen; P. van Gelderen; J. H. N. Creyghton; W. M. M. J. Bovée
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 375 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
It is shown that the signal of intracellular and extracellular sodium of red blood cells can be separated by a difference in diffusion. Comparison with proton diffusion experiments conducted in parallel showed that this difference was caused by restriction to the cell volume. The measured proton and sodium root mean square displacements agreed well with the cell dimensions. However, this experiment is limited to use in vitro by the required gradient strength.
📜 SIMILAR VOLUMES
23 Na double-quantum-filtered (DQF ) NMR enables the detecfound between the residual quadrupolar interaction and the tion of anisotropic motion of sodium ions due to their interaction conformation of the cytoskeleton (3, 4). In the present study with ordered structures in biological tissues. Using t