Differing effects of NG-monomethyl L-arginine and 7-nitroindazole on detrusor activity

Effects of different bile salts on stead

Effects of different bile salts on steady-state mRNA levels and transcriptional activity of cholesterol 7α-hydroxylase

✍ William M. Pandak; Z. Reno Vlahcevic; Douglas M. Heuman; Kaye S. Redford; John Y 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 822 KB

Cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid synthesis pathway, is downregulated by taurocholate by way of negative feedback control at the level of gene transcription. The molecular basis of regulation of cholesterol 7cy-hyhxylase by other hydrophobic bile salts and under m