## Abstract Cues from the material to which a cell is adherent (e.g., adhesion ligand presentation, substrate elastic modulus) clearly influence the phenotype of differentiated cells. However, it is currently unclear if stem cells respond similarly to these cues. This study examined how the overall
Differentiation stage alters matrix control of stem cells
β Scribed by Susan X. Hsiong; Paolo Carampin; Hyun-Joon Kong; Kuen-Yong Lee; David J. Mooney
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 26 KB
- Volume
- 87A
- Category
- Article
- ISSN
- 1549-3296
No coin nor oath required. For personal study only.
β¦ Synopsis
The authors have brought to our attention an error in the figure legend for Figure 5E (the mRNA gel image). The correct version for Figure 5E should be: (E) Osteogenic differentiation was also assessed at the genetic level using reverse-transcriptase PCR. Osteocalcin mRNA levels were upregulated in samples cultured in the presence of osteogenic supplements (lane 3 [day 14]), as compared to samples cultured in media only (lane 1 [day 3] and 2 [day 14]). We regret any confusion caused by this error.
π SIMILAR VOLUMES
Embryonic stem cells (ESCs) are pluripotent and have the ability to differentiate into mineralising cells in vitro. The use of pluripotent cells in engineered bone substitutes will benefit from the development of bioactive scaffolds which encourage cell differentiation and tissue development. Extrac
## Abstract Mesenchymal stem cells (MSCs) respond to a variety of differentiation signal provided by their local environments. A large portion of these signals originate from the extracellular matrix (ECM). At the same time, MSCs secrete various matrixβaltering agents, including proteases, that alt