✦ LIBER ✦

Controlling Differentiation of Neural Stem Cells Using Extracellular Matrix Protein Patterns

✍ Scribed by Aniruddh Solanki; Shreyas Shah; Kevin A. Memoli; Sung Young Park; Seunghun Hong; Ki-Bum Lee

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 957 KB
Volume: 6
Category: Article
ISSN: 1613-6810
DOI: 10.1002/smll.201001341

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Extracellular matrix-mediated osteogenic

Extracellular matrix-mediated osteogenic differentiation of murine embryonic stem cells

✍ Nicholas D. Evans; Eileen Gentleman; Xinyong Chen; Clive J. Roberts; Julia M. Po 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 989 KB

Embryonic stem cells (ESCs) are pluripotent and have the ability to differentiate into mineralising cells in vitro. The use of pluripotent cells in engineered bone substitutes will benefit from the development of bioactive scaffolds which encourage cell differentiation and tissue development. Extrac

Differentiation stage alters matrix cont

Differentiation stage alters matrix control of stem cells

✍ Susan X. Hsiong; Paolo Carampin; Hyun-Joon Kong; Kuen-Yong Lee; David J. Mooney 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 26 KB

The authors have brought to our attention an error in the figure legend for Figure 5E (the mRNA gel image). The correct version for Figure 5E should be: (E) Osteogenic differentiation was also assessed at the genetic level using reverse-transcriptase PCR. Osteocalcin mRNA levels were upregulated in

Differentiation stage alters matrix cont

Differentiation stage alters matrix control of stem cells

✍ Susan X. Hsiong; Paolo Carampin; Hyun-Joon Kong; Kuen-Yong Lee; David J. Mooney 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 618 KB

## Abstract Cues from the material to which a cell is adherent (e.g., adhesion ligand presentation, substrate elastic modulus) clearly influence the phenotype of differentiated cells. However, it is currently unclear if stem cells respond similarly to these cues. This study examined how the overall

Neural differentiation regulated by biom

Neural differentiation regulated by biomimetic surfaces presenting motifs of extracellular matrix proteins

✍ M. J. Cooke; T. Zahir; S. R. Phillips; D. S. H. Shah; D. Athey; J. H. Lakey; M. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 925 KB

## Abstract The interaction between cells and the extracellular matrix (ECM) is essential during development. To elucidate the function of ECM proteins on cell differentiation, we developed biomimetic surfaces that display specific ECM peptide motifs in a controlled manner. Presentation of ECM doma

Interactive effects of mechanical stretc

Interactive effects of mechanical stretching and extracellular matrix proteins on initiating osteogenic differentiation of human mesenchymal stem cells

✍ Chien-Hsun Huang; Min-Huey Chen; Tai-Horng Young; Jiiang-Huei Jeng; Yi-Jane Chen 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB 👁 1 views

## Abstract Human mesenchymal stem cells (hMSCs) are characterized by their abilities to differentiate into different lineages, including osteoblasts. Besides soluble factors, mechanical strain and extracellular matrix (ECM) proteins play important roles in osteogenic differentiation of hMSCs. Howe

Sortilin is upregulated during osteoblas

Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization

✍ Shingo Maeda; Takahiro Nobukuni; Kazuki Shimo-Onoda; Kyoji Hayashi; Kazunori Yon 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 225 KB 👁 1 views

Osteoblasts and adipocytes are derived from a common precursor in bone marrow, the mesenchymal stem cell (MSC). Factors driving human MSCs (hMSCs) to differentiate down the two lineages play important roles in determining bone density because it has been shown that bone volume loss associated with o