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Differentiation of embryonic stem cells into cardiomyocytes induced by leukemia inhibitory factor (LIF)

โœ Scribed by Petrova, R. R. ;Mezhevikina, L. M. ;Fesenko, E. E.


Book ID
110155713
Publisher
Biophysical Society of Japan
Year
2006
Tongue
English
Weight
262 KB
Volume
51
Category
Article
ISSN
1349-2942

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The cardiomyocyte (CM) differentiation of embryonic stem cells (ESCs) is routinely cultured as two-dimensional (2D) monolayer, which doesn't mimic in vivo physiological environment and may lead to low differentiated level of ESCs. Here, we develop a novel strategy that enhances CM differentiation of