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Differentiation and apoptosis induction therapy in acute promyelocytic leukaemia

โœ Scribed by Zhen-Yi Wang; Zhu Chen


Book ID
117782012
Publisher
The Lancet
Year
2000
Tongue
English
Weight
611 KB
Volume
1
Category
Article
ISSN
1470-2045

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Acute promyelocytic leukemia (APL) is a subset of acute myeloid leukemia characterized by the morphology of the blast cells (M3 type in the FAB nomenclature), and a specific t(15;17) translocation. APL was further characterized by a specific sensitivity to all-trans retinoic acid's differentiation e