Unstable GTP cyclohydrolase I (GCH) mutations in dopa-responsive dystonia (DRD) can exert a dominant-negative effect in the HeLa cell model, but in a batch of cells this effect could not be shown. Through differential display, we found a higher Hsc70 expression in the non-dominant-negative cells. We
β¦ LIBER β¦
Differential Splicing of the GTP Cyclohydrolase I RNA in Dopa-Responsive Dystonia
β Scribed by Makito Hirano; Yasuyuki Imaiso; Satoshi Ueno
- Book ID
- 115580257
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 301 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0006-291X
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