Synaptosomal-associated protein of 25 kDa (SNAP-25) is involved in the molecular regulation of neurotransmitter release. SNAP-25 exists in two isoforms, SNAP-25a and SNAP-25b, which arise from alternate splicing and which are differentially expressed throughout the nervous system. In situ hybridizat
✦ LIBER ✦
Differential sorting of SNAP-25a and SNAP-25b proteins in neuroblastoma cells
✍ Scribed by Johan Andersson; Gabriel Fried; Lena Lilja; Björn Meister; Christina Bark
- Book ID
- 114493101
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 184 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0171-9335
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SNAP-25 and Rab3A were originally identified as synaptic proteins involved in neuronal membrane traffic. Recently, both proteins have been detected in several mammalian endocrine cell types and have been proposed as essential components of the exocytotic pathway in neuroendocrine cells. In this stud