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Differential sensitivity of antinociceptive assays to the bradykinin antagonist Hoe 140

✍ Scribed by Christopher G. Heapy; John S. Shaw; Susannah C. Farmer


Book ID
117959849
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
832 KB
Volume
108
Category
Article
ISSN
0007-1188

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πŸ“œ SIMILAR VOLUMES


Synthesis of the bradykinin B1antagonist
✍ Paolo Rovero; Stefania ViganΓ²; Stefano Pegoraro; Laura Quartara πŸ“‚ Article πŸ“… 1996 πŸ› Springer Netherlands 🌐 English βš– 327 KB

This paper describes the synthesis of the bradykinin B l antagonist [desArglΒ°]HOE 140 (D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-OH) by the solid-phase method. This synthesis is predicted to be a difficult one because the Cterminal sequence D-Tic-Oic, when linked to the resin, could easily undergo an